Issue:Comparison of different mathematical models of an E. coli fed-batch cultivation process using a generalized net model

shortcut

http://ifigenia.org/wiki/issue:iwgn-13-15-23

Title of paper: Comparison of different mathematical models of an E. coli fed-batch cultivation process using a generalized net model Author(s): Dimitar Dimitrov Faculty of Mathematics and Informatics, Sofia University, 5 James Bourchier Str., Sofia, Bulgaria Department of Bioinformatics and Mathematical Modelling, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 105 Acad G. Bonchev Str., 1113 Sofia, Bulgaria dgdimitrov@fmi.uni-sofia.bg Olympia Roeva Department of Bioinformatics and Mathematical Modelling, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 105 Acad G. Bonchev Str., 1113 Sofia, Bulgaria olympia@biomed.bas.bg Presented at: 13th IWGN, London, 29 October 2012 Published in: Conference proceedings, pages 15—23 Download:  PDF (240  Kb, File info) Abstract: In this paper, a generalized net model for comparison of different mathematical models of an E. coli fed-batch cultivation process is developed. The herewith proposed GN model is simulated using GN Lite – a software package for modeling and simulation with GNs. The GN model compares the set of mathematical models of a considered cultivation process and chooses, based on a predefined criterion, the best process model. During the simulation, the GN model calls the Matlab software environment to solve the process model, presented as a system of nonlinear differential equations. In the end of the simulation, the software package plots the main process variables’ dynamics with time. Keywords: Generalized net, GN Lite, GNTicker, GN IDE, E. coli, Fed-batch cultivation, Mathematical models. AMS Classification: 68Q85. References: Aladjov, H., K. Atanassov. A Generalized Net for Genetic Algorithms Learning, Proc. of the XXX Spring Conference of the Union of Bulgarian Mathematicians, Borovets, Bulgaria, April 8-11 2001, 242–248. Atanassov, K. Generalized Nets, World Scientific, Singapore, 1991. Atanassov, K. Generalized Nets and Systems Theory, “Prof. M. Drinov” Academic Publishing House, Sofia, 1997. Atanassov, K., H. Aladjov. Generalized Nets in Artificial Intelligence. Volume 2: Generalized Nets and Machine Learning, “Prof. M. Drinov” Academic Publishing House, Sofia, 2000. Atanassov, K. On Generalized Nets Theory, “Prof. M. Drinov” Academic Publishing House, Sofia, 2007. Dimitrov, D. G. GN IDE - A Software Tool for Simulation with Generalized Nets, Proc. of Tenth Int. Workshop on Generalized Nets, Sofia, 5 December 2009, 70–75. Dimitrov, D. G. A Graphical Environment for Modeling and Simulation with Generalized Nets. Annual of “Informatics” Section, Union of Scientists in Bulgaria, Vol. 3, 2010, 51–66 (In Bulgarian) Dimitrov, D. G. Software Products Implementing Generalized Nets. Annual of ”Informatics” Section, Union of Scientists in Bulgaria, Vol. 3, 2010, 37–50 (In Bulgarian). Dimitrov, D. G. Integration of the Generalized Nets Simulator GNTicker with MATLAB. Annual of ”Informatics” Section, Union of Scientists in Bulgaria, Vol. 4, 2011, 49–52 (In Bulgarian). Georgieva, O., I. Hristozov, T. Pencheva, St. Tzonkov, B. Hitzmann. Mathematical Modelling and Variable Structure Control Systems for Fed-batch Fermentation of Escherichia coli, Chemical and Biochemical Engineering Quarterly, Vol. 17, 2003, No. 4, 293–299. Kosev, K., T. Trenkova, Roeva O. Tabu Search for Parameter Identification of an Fermentation Process Model, Journal of International Scientific Publication: Materials, Methods & Technologies, Vol. 6, 2012, No. 2, 457–464. Roeva, O. Generalized Net Model of Oxygen Control System using Intuitionistic Fuzzy Logic, Proceedings of the 1st International Workshop on Intuitionistic Fuzzy Sets, Generalized Nets and Knowledge Engineering, University of Westminister, London, UK, 6-7 September 2006, 49–55. Roeva, O., T. Pencheva. Generalized Net for Control of Temperature in Fermentation Processes, Issues in Intuitionistic Fuzzy Sets and Generalized Nets, Wydawnictwo WSISiZ, Warszawa, Vol. 4, 2007, 49–58. Roeva, O., T. Pencheva, St. Tzonkov. Generalized Net for Proportional-Integral-Derivative Controller, In Book Series: “Challenging Problems of Sciences” - Computer Sciences, 2008, 241–247. Roeva, O. Parameter Estimation of a Monod-type Model based on Genetic Algorithms and Sensitivity Analysis, Lecture Notes on Computer Science, Springer-Verlag Berlin Heidelberg, Vol. 4818, 601–608. Roeva, O. Optimization of E. coli Cultivation Model Parameters Using Firefly Algorithm, Int. J. Bioautomation, Vol. 16, 2012, No. 1, 23–32. Shannon, A., O. Roeva, T. Pencheva, K. Atanassov. Generalized Nets Modelling of Biotechnological Processes, “Prof. M. Drinov” Academic Publishing House, Sofia, 2004. Trifonov, T., K. Georgiev. GNTicker - A software tool for efficient interpretation of generalized net models, Issues in Intuitionistic Fuzzy Sets and Generalized Nets, Vol. 3, 2005, 71–78. Trifonov, T., K. Georgiev, K. Atanassov. Software for modelling with Generalised Nets, Issues in Intuitionistic Fuzzy Sets and Generalized Nets, Vol. 6, 2008, 36–42. Citations: Issue:Development of a Generalized Net for Comparison of Different Models Obtained using Metaheuristic Algorithms ‎ (← links) The list of publications, citing this article may be empty or incomplete. If you can provide relevant data, please, write on the talk page.